Acute graft versus host disease is a rare but deadly complication following liver transplantation.Author show here, upon screening a large cohort of liver CHANCA PIEDRA transplanted patients and detailed immune phenotyping of samples from the 7 affected individuals and appropriate controls, that human T cell lymphotropic virus type I infection of d
In recent times, Artificial Intelligence (AI) has become ubiquitous in technological fields, mainly due to its ability to perform computations in distributed systems or the cloud.Nevertheless, for some applications -as the case of EMG signal processing- it may be highly advisable or even mandatory an on-the-edge processing, i.e., an embedded proces
Abstract Background Aldo-keto reductase family 1 member C3 (AKR1C3) is a radioresistance gene in esophageal cancer.This study aimed to investigate the signaling pathways that mediate the regulatory role of AKR1C3 in the radioresistance of esophageal cancer cells.Methods The protein levels of AKR1C3 in cancer tissue samples were compared between pat
Neuromorphic event-driven systems emulate the computational mechanisms of the brain through the utilization of spiking neural networks (SNN).Neuromorphic systems serve two primary application domains: simulating neural information processing in neuroscience and acting as accelerators for cognitive computing in engineering applications.A distinguish
Phenotypic screening is an ideal strategy for the discovery of novel bioactive molecules.Using a customized high-throughput screening (HTS) assay employing primary T lymphocytes, we screened a small library of 4,398 compounds with unknown biological function/target to identify compounds eliciting immunomodulatory properties and discovered a sulfony